Preheat your oven to 425°F (220°C) to ensure it's hot and ready for roasting.
In a large mixing bowl, combine the cauliflower florets with olive oil, garlic powder, onion powder, smoked paprika, salt, and pepper. Toss thoroughly until each floret is well coated in the seasoning mixture.
Spread the seasoned cauliflower in an even layer on a baking sheet. Roast in the preheated oven for approximately 20 minutes, stirring the florets halfway through the cooking time, until they are golden brown and tender to the fork.
Once roasted, carefully remove the baking sheet from the oven. Place the cauliflower in a bowl and toss them in buffalo sauce until every piece is fully coated. Return the sauced cauliflower to the baking sheet and roast for an additional 10 minutes to enhance the flavor.
Take your pre-made pizza crust and spread ½ cup of buffalo sauce evenly across the surface. Layer the roasted buffalo cauliflower on top of the sauce, ensuring an even distribution. Then, sprinkle the shredded mozzarella cheese generously over the cauliflower. If you’re using blue cheese, sprinkle it over the top for an extra tangy flavor kick.
Carefully place the assembled pizza in the oven and bake for 12-15 minutes, or until the cheese is melted and bubbling in the center. Keep an eye on it to prevent over-browning.
Once baked to perfection, take the pizza out of the oven and let it cool for a few minutes. Before slicing, garnish with freshly chopped parsley to add a pop of color and freshness. Serve warm and enjoy the delicious flavors!